منابع مشابه
Biogenesis of rosmarinic acid in Mentha.
The biogenesis of rosmarinic acid (alpha-O-caffeoyl-3,4-dihydroxyphenyl-lactic acid), the second most common ester of caffeic acid in the plant kingdom, was studied in Mentha arvense and Mentha piperita. Administration of (14)C-labelled compounds showed that, whereas the caffeoyl moiety was formed from phenylalanine via cinnamic acid and p-coumaric acid, the 3,4-dihydroxyphenyl-lactic acid moie...
متن کاملEnvironmental Factors Affecting the Accumulation of Rosmarinic Acid in Spearmint (Mentha spicata L.) and Peppermint (Mentha piperita L.)
Four spearmint, and two peppermint clonal lines, selected for enhanced rosmarinic acid content (50-120 mg g -1 rosmarinic acid DW), where up to 80% of the antioxidant activity was correlated to rosmarinic acid content, were examined to determine the effects of environmental and physiological conditions on the accumulation of rosmarinic acid in leaf tissues. Exposure to a short photoperiod of 12...
متن کاملEnhanced rosmarinic acid production in cultured plants of two species of Mentha.
In the present investigation an attempt has been made to enhance rosmarinic acid level in plants, grown in vitro, of 2 species of Mentha in presence of 2 precursors in the nutrient media during culture. For in vitro culture establishment and shoot bud multiplication, MS basal media were used supplemented with different concentrations and combinations of different growth regulator like NAA (alph...
متن کاملMetabolic modeling of Rosmarinic acid biosynthetic pathway
Rosmarinic acid (RA) is an ester of caffeic acid and 3, 4-dihydroxyphenyllacticacid. It is commonly found in Coleus blumei, Salvia officinalis, Melissa officinalis and Rosmarinus officinalis. The biosynthesis of RA starts with precursor molecules L-phenylalanine and L-tyrosine. Simulation of RA biosynthetic pathway was done using Gepasi Software, includes the reaction kinetics of each step of t...
متن کاملRosmarinic acid potentiates carnosic acid induced apoptosis in lung fibroblasts
Pulmonary fibrosis is characterized by over-population and excessive activation of fibroblasts and myofibroblasts disrupting normal lung structure and functioning. Rosemary extract rich in carnosic acid (CA) and rosmarinic acid (RA) was reported to cure bleomycin-(BLM)-induced pulmonary fibrosis. We demonstrate that CA decreased human lung fibroblast (HLF) viability with IC50 value of 17.13±1.0...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1970
ISSN: 0306-3283
DOI: 10.1042/bj1180291